Technologies

AFM systems fully tailored to your specifications

• Meeting to understan your requirements
• Nansosurf outlines solution
• joint discussion of solution,
• adaptation solution concept
• order based on concept

• Cylindrical mirror analyzer (CMA)
• Coaxial 25 kV field emission electron gun
• Scintillation secondary electron detector
• High energy resolution module
• 5 axis automated sample stage
• 5 kV floating column Ar⁺ ion gun
• SmartSoft-Auger instrument control software
• MultiPak data reduction software
• Acoustic Enclosure
• Ion pumped main chamber

• TRIFT mass analyzer
• 30 kV LMIG with Bi, Au, or Ga emitter
• Dual beam charge neutralization
• 5 axis sample stage
• In-situ optical viewing
• Secondary electron detector
• WinCadence instrument control and data reduction software package
• Analysis chamber with four primary ion gun ports
• 350 l/s turbo molecular pump
• Integrated bakeout facilities
• MS/MS ready spectromoter

• To Flow Cell – Headless Nut 10-32 for 1/6″ O.D. Tubing
• Total Volume: 25µL (Volume occupied by Counter Electrode 7uL) Wetted Materials
• Tubing – PEEK™
• Flow Cell – Acetal Copolymer (Delrin)
• Counter Electrode – Platinum
• Working Electrode – Gold SPR Sensor Slide
• Reference Electrode – Ceramic Porous Junction

• Provides easy adaptability to MALDI mass spectrometry
• Important in ligand fishing experiments
• Sensor chip is not compromised

• Throughput range 0.4 kg/h to 20 kg/h (material dependent)
• Segmented screw design and removable top half barrel
• A screw length adjustment kit enables small quantity compounding
• A fully ported barrel allows maximum flexibility for feeding and degassing
• Contact parts selectable from three steel grades
• An easy-to-operate touch screen with integrated feeder control
• Broad accessory portfolio, e.g.. dies, feeders, water bath, conveyor belt, strand or die face pelletizers, haul off, and spooler
• The granulation kit enables customers to switch between melt extrusion and wet/melt granulation
• Geometrically scalable screw and barrel design across portfolio

• Co- and counter-rotating twin screws
• Integrated viscosity measurement (with HAAKE PolySoft OS)
• Automatic bypass operation for circulation/extrusion
• Pneumatic feeding
• Local control via tablet (Android®) for  intuitive operation
• Split barrel exit for easy cleaning
• Compact enough to fit into laboratory fume hood’

• Minimized sample material usage (20 g)
• Throughput range 20g/h to 2.5kg/h
• Small footprint bench top design that is easily transportable
• Segmented screw design with removable top half barrel
• Easy-to-operate touch screen with integrated feeder control
• Geometrically scalable screw and barrel design across portfolio

• Throughput range 0.4 kg/h to 20 kg/h (material dependent)
• Segmented screw design and removable top half barrel
• A screw length adjustment kit enables small quantity compounding
• A fully ported barrel allows maximum flexibility for feeding and degassing
• Contact parts selectable from three steel grades
• An easy-to-operate touch screen with integrated feeder control
• Broad accessory portfolio, e.g.. dies, feeders, water bath, conveyor belt, strand or die face pelletizers, haul off, and spooler
• The granulation kit enables customers to switch between melt extrusion and wet/melt granulation
• Geometrically scalable screw and barrel design across portfolio

• Horizontally split barrel (up to 40:1 L/D) is hinged for easy access to the screws; simple screw removal device promotes quick and easy cleaning and configuration changes
• Barrel is constructed in segmented modules that can be reconfigured to suit a variety of polymer processes
• Replaceable barrel liners can be made from special materials for abrasive or aggressive applications
• Barrel segments are available for feeding solids and liquids or for venting
• Secondary feeders and vacuum pumps can also be incorporated into the system
• Powerful control software is programmed to recognize plug-in ancillaries
• Large color touch screen interface incorporates on-screen, real-time trend display

• Uses smaller material quantities for faster, cost-effective development
• Converts easily from hot melt extrusion (HME) to twin screw granulation (TSG) applications
• Operates at throughput ranges from 20g/h up to 2.5kg/h
• Processing length: L/D ratio 40:1
• Screw elements and barrel design scale geometrically across the all Thermo Scientific Pharma Extruders and allow easy process scale-up
• Easy-to-operate with user-friendly, intuitive touch screen with integrated feeder control
• Maximize lab space with small footprint machine
• Perfect for glove box or isolator applications with removable touch screen
• All material contact parts are easily removable
• Documentation of extrusion parameters and suitable for process analytical technology (PAT)
• GMP-compliant, full validation available: FAT, SAT, IQ/OQ

• 2-in-1 process design – quickly disassemble parts for easy cleaning and process switching from HME to TSG.
• Simple continuous process integration – plug-and-play functionality with upstream and downstream process equipment (e.g., feeders, chill rolls, pelletizers, dryers, etc) simplifies production line design.
• Less optimization time, cost and effort – extruder process parameters are scaleable to larger Thermo Scientific extruders due to geometric similarity with minimal use of expensive ingredients.

The HAAKE PolyLab QC Modular Torque Rheometer Features:
Backward Compatibility

• Compatible with previous model mixers and extruders
• Adapts to existing accessories for use
• Imports previous data for compatibility

• Extrudability of newly developed materials
• Manufacturing homogeneous melts
• Manufacturing films, foils, strands and profiles for optical and mechanical testing as well as outdoor exposure tests
• Measuring rheological behavior (viscosity, elasticity)
• Testing individual and combined influences of additives (stabilizer, lubricant) and functional additives (anti-oxidation, UV-stabilizers, pigments and fillers)
• Foam extrusion

Overcome drug formulation challenges

Pharmaceutical manufacturers are using conical and twin-screw extruders to mix drug molecules with bioactive polymers in situations where drug ingredients are poorly soluble or unstable during processing. Extruders are also useful in preparing enteric dosages, sustained release dosages, in taste-masking, and to create forms such as films.