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Single Cell Research

Sphere Fluidic’s technology makes it possible to encapsulate and screen millions of individual cells or biological molecules in a single day. This enables you to find that rare or valuable cell variant, whether it’s a diseased cell, a high producer or even a valuable biological product. Processing millions of samples or cells a day, our technology is perfect for a variety of high throughput screening applications. We work with Sphere Fluidics in this technology.

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  • Cyto-Mine® – Antibody discovery and cell line development workflows streamlined like never before

    • Targeted Discovery – .Rapidly identify and isolate your rare cells of interest.
    • Monoclonality Assurance – Extensive proof of monoclonality for cell line development.
    • Significantly Reduce Timelines and Costs – Tens of millions of cells in pools or hundreds of thousands individually are screened in a single day.
    • Flexibility – Flexible assay design allows quantitative measurement of antibody secretion.
    • Sterility – The entire process is automated, sterile and Animal Origin Free. The Benchtop system is compatible for use in Class II biosafety cabinets.

     

  • Cyto-Mine® – Antibody discovery and cell line development workflows streamlined like never before

    • Targeted Discovery – .Rapidly identify and isolate your rare cells of interest.
    • Monoclonality Assurance – Extensive proof of monoclonality for cell line development.
    • Significantly Reduce Timelines and Costs – Tens of millions of cells in pools or hundreds of thousands individually are screened in a single day.
    • Flexibility – Flexible assay design allows quantitative measurement of antibody secretion.
    • Sterility – The entire process is automated, sterile and Animal Origin Free. The Benchtop system is compatible for use in Class II biosafety cabinets.

     

    • Semi-automated – Modular system for analysis of single cells or biomolecules in picodroplets.
    • High-throughput – High-speed processing, detection and sorting of picodroplets (up to 12,000 per minute).
    • Measure secreted proteins – Enables sensitive detection of secreted proteins (e.g. cytokines, antibodies, enzymes).
    • Choice of parameters – User-defined microfluidic flow rates, picodroplet size, gating settings.
    • Multiple detection modes – Range of optical detection methods (fluorescence, luminescence & scatter).

     

    • Optimized for use with Pico-Surf™ and our other specialist chemicals
    • Compatible with our range of Pico-Gen™ microfluidic biochips.
    • Especially formulated to be biocompatible and stable.
    • High purity and long shelf life (up to one year).
    • Animal Origin Free.
    • Experienced scientific and application support available.
    • Volume – 100 ml, 250 ml, 500 ml

     

  • Pico-Break™ is used to used to gently reduce the stability of picodroplets in order to release cellular or molecular contents into an aqueous medium for subsequent processing.

    Volume 10ml, 50ml
    Features 1. Allows gentle breaking of picodroplets (by phase separation via chemically-induced coalescence).
    2. Compatible with picodroplets stabilised by Pico-Surf™ surfactants.
    3. Contains a dye to visually confirm recovery of sample material.

     

  • Pico-Glide™ is a coating agent designed for users who manufacture their own microfluidic biochips using plasma etched glass or PDMS.

    Volume 5ml, 10ml, 25ml
    Features 1. A specialised chemical solution to promote consistent in-house manufacture of microfluidic biochips.
    2. Minimises non-specific binding interactions.
    3. Improves picodroplet performance and stability.

     

  • – A reliable, high-performing surfactant for droplet microfluidics

    • Biocompatibility– designed for generating aqueous picodroplets in oil
    • Highest droplet stability– shown by assessment of picodroplet fusion, interfacial tension and critical micelle concentration
    • Stability at high temperature– demonstrated by the low level of picodroplet fusion
    • Low voltage for droplet sorting– purity and quality of the surfactants enables a more efficient sorting process
    • Excellent batch-to-batch reproducibility– all products undergo rigorous QC and QA testing to ensure batch consistency
    • Unique and patented molecular surfactant structure – patent freedom to operate in a wide range of application areas.
    • Specialist expertise and support– our team brings extensive experience and support to guide your applications

     


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Contact Spectra Research

Address

3585 Laird Rd., Unit 15 & 16,
L5L 5Z8 Mississauga
Ontario
Canada

Phone :  905-890-0555

Toll Free : 1-866-753-4433
Fax :  905-890-1959

Email: info@spectraresearch.com

About Spectra Research

Spectra Research Corporation (SRC) offers a range of innovative high-quality scientific products and laboratory services to industrial and scientific markets throughout Canada.

Established in 1993, SRC is a subsidiary of Allan Crawford Associates (ACA), one of Canada’s largest distributors of electronic components, test equipment and integrated networking solutions.

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