DLS at High Concentration

Dynamic Light Scattering (DLS) is an effective measurement technique used for measuring the hydrodynamic size of common nanomaterials including colloids, nanoparticles, proteins, and polymers. Despite the versatility of this technique, there are several important considerations that cannot be ignored when using light scattering to characterize high-concentration solutions. While it is possible to make measurements on high volume-fraction samples without dilution, it raises additional questions about the meaning of the hydrodynamic size. To understand why this is the case we need to discuss two effects encountered in concentrated solutions: multiple scattering and mutual diffusion.

Download the PDF White Paper to Learn More


Workshop : Hybrid Nano-lithography Technology combining Thermal SPM and Direct Laser Lithography

Hybrid Nano-lithography Technology_1

SwissLitho commercialized tSPL

This fall SwissLitho is releasing its newest product “NanoFrazor Explore DLS“. This unique hybrid nano-micro lithography system, which combines thermal Scanning Probe Lithography (tSPL) with Direct Laser Sublimation (DLS) was developed by Heidelberg Instruments and SwissLitho.

SwissLitho commercialized tSPL out of IBM Research in 2014 and its commercial NanoFrazor systems are installed at various institutions and used for the fabrication of nanodevices when usual nanolithography techniques get complicated or fail.

You are cordially invited to this workshop which aims to introduce the capabilities of the technologies of Heidelberg Instruments and SwissLitho and discuss their opportunities for McGill University researchers.

Date and time: 1:30 pm, Sept 17th, 2019

Place/Room: Rutherford Physics building, RM 105, 3600 University street

1:30 pm NanoFrazor lithography – an overview
1:55 pm
NanoFrazor DLS – mix&match lithography in the same resist and same system
2:20 pm
Overview on various pattern transfer processes for NanoFrazor lithography
2:45-3:00 pm
Open user discussion
3:00-5:00 pm
Live System demo in CR

SRC logoWe are looking forward to seeing you at our workshop!

For more information please contact : Serge Dandache
Hybrid Nano-lithography


lithography Technology

Compounding solutions for 3D filament production

Optimize formulation and production in fewer steps

With the popularity of 3D printing new polymer formulations need to be tested in order to meet the demands of new product applications for industries such as aerospace, medical devices, and automotive. Consequently, polymer compounding for the production of novel 3D filaments becomes a critical step in the workflow for designing successful 3D printing applications.

Advantages of twin-screw extrusion for fused filament fabrication (FFF)

The Thermo Scientific™ Process 11 Twin-screw Extruder and the Thermo Scientific™ HAAKE™ PolyLab OS Rheomex PTW Twin-screw Extruder offer significant benefits over single-screw extruders for 3D filament development to help:

  • Minimize or eliminate the effects of coalescence to maintain particle size distribution
  • Avoid a second heat history when processing heat sensitive polymers
  • Improve layer-to-layer adhesion with uniform binder dispersion
  • Avoid time and energy consumption by eliminating the need to dry hygroscopic materials
  • Reduce waste of expensive additives like pharma excipients, graphene and metals

Thermo Scientific™ Process 11 Lab-scale 3D Filament Production System Process 11 Lab-scale

Use this compact benchtop solution for research-scale formulation and process development. Figure 1 shows this system with:

  • Process 11 Twin-screw Extruder
  • Thermo Scientific™ Process 11 Melt Pump
  • Filament spooler

From 20 g/h up to 2 kg/h throughput, this system is ideal for development of new compounding processes. Easy to operate this system provides process data that supports the scaling up of your 3D filament production process, while reducing the amount of expensive raw material during formulation development

FL53142-3D Filament Systems Promo-EN-FL-53142-FINAL



Reduce 3D filament development time

Streamline 3D filament development by combining compounding and filament formation in one system. Based on our twin-screw extruders, we have designed two systems that allow you to quickly test different formulations and produce spooled 3D filaments in fewer steps than traditional workflows. Both systems produce filaments directly from the compounding process by using a melt pump for pulsation-free output, which ensures a precise filament diameter and significantly reduces time and labor costs. The thermal stress on the filament material is also reduced by eliminating unnecessary heat-cool cycles that occur if mixing and filament production are separated.

Thermo Scientiἀc™ HAAKE™ PolyLab Pilot-scale 3D Filament Production System

Use this system for lab-to-small scale process development and production. Figure 2 shows this system with:

  • HAAKE PolyLab OS Rheomex PTW Twin-screw Extruder
  • Thermo Scientiἀc™ Melt Pump for the OS Rheomex Extruder
  • Filament spooler on a mobile bench

Reach material throughputs of up to 5 kg/h with this system that includes the ability to characterize new material compounds with mixer tests and capillary rheology.







FREE WITec Workshop August 8, 2019, University of Guelph

Increase Your WiTec Knowledge

Presented in cooperation with the Food Science department at the University of Guelph, topics will include theory, 3D imaging, New application and research by local universities.



About WITech WITec is a manufacturer of high-resolution optical and scanning probe microscopy solutions for scientific and industrial applications. The company’s product line features scanning near-field optical microscopy using unique cantilever technology, confocal Raman Imaging and Scanning Electron Microscopy designed for the highest sensitivity and resolution, and Atomic Force Microscopy (AFM) for materials research and nanotechnology. The modular design of WITec microscopes allows the combination of these techniques. Thus not only chemical information, but also structural and topographic information can be acquired at the same time and on the same sample area using one instrument and one operating system—all from the same manufacturer. WITec’s innovations in SpectroscopyMaterials Characterization and Atomic Force Microscopy continue to redefine what is possible for a wide variety of optical, structural, and chemical imaging techniques.

About Spectra Research Corporation (SRC)

SRC is Canada’s premier source for innovative high-quality scientific products and laboratory services to industrial and scientific markets in Canada. Through continuous improvement and quality practices, SRC provides clients with exceptional laboratory services and support. An ISO9001-registered company, SRC delivers technical expertise and industry knowledge for all of the products represented.

Webinar with Nanosurf on cell manipulation with FluidFM®

Wiley and Nanosurf are holding a webinar about the current research possibilities using FluidFM technology in the areas of single cell injection, extraction, and deposition, with sub-picoliter accuracy.

Single Cell Injection, Deposition and Aspiration

Force controlled manipulation with FluidFM®

Thursday, 27 June 2019 | 2 p.m. (CEST)

Who should attend the Webinar:
Cell biologists, biophysicists, nano scientists, scientists working with CRISPR.

Key Learning Objectives:

  • Understand FluidFM technology and its application areas, limits, and possibilities
  • Understand the differences between FluidFM and other micromanipulation techniques
  • Learn about the benefits of force control for micromanipulation
  • Learn how cell stimulation by local deposition of chemical stimuli works
  • Understand how to inject into and extract material from a cell or its nucleus without sacrificing it
  • Learn with which optical techniques FluidFM can be combined, and for what purpose

Ne Manquez Pas de Voir en Action la Bio-Imprimante 3D BioX de Cellink!

Nous sommes ravis de vos inviter au Séminaire et Atelier sur la Nouvelle Bio-Imprimante 3D et sur les Encres Biologiques BioInks de Cellink.

La BioX est conçue et produite par Cellink, le chef de file de la Bio- Impression 3D. Notre équipe vous présentera les caractéristiques uniques de la BioX et des encres biologiques BioInks que tous les chercheuses/chercheurs en Science de la Vie attendaient.


Bio-Imprimante 3D BioX de Cellink

Mardi 7 mai 2019
entre 13h30 et 17h00

Université de Montréal
Pavillon Jean-Coutu,
Salle S1-125
Cliquez ici pour vous inscrire

Come and bring your colleagues to discuss your research applications and to get access to the BioX.  And don’t forget to spread the word through your network. Contact Spectra Research Corporation, the distributor of Cellink 3D BioPrinters and BioInks, today: Contact Us 

Venez nombreux pour discuter de vos applications et gagner accès à la BioX. N’oubliez pas de faire passer le mot à vos collègues et collaborateurs. Contactez des aujourd’hui Spectra Research Corporation, le distributeur des Bio-Imprimantes 3D et encres biologiques BioInks de Cellink: Contactez nous


New Generation Theta Optical Tensiometer from Biolin Scientific

Optical tensiometer; Smart interfacial measurement solutions for wettability and adhesion

The new generation Theta Optical Tensiometer (Attension® Theta Flex) from Biolin Scientific  is a contact angle meter that enables all measurements in one instrument for both research and quality control. It measures static and dynamic contact angle, 3D surface roughness, surface free energy, surface and interfacial tension, and interfacial rheology.

Theta Optical Tensiometer
Theta Optical Tensiometer

One instrument for all your measurement needs

All the measurements are readily included in the software. Thanks to the modular design, all applications can be fulfilled with one instrument and the instrument can be tailored for your needs.

Results you can rely on

High-end imaging together with sophisticated analysis algorithms detect and analyze the contact angle and surface free energy precisely. The effect of roughness to wettability can be measured with the unique 3D Topography module.

Speed and repeatability

All steps from loading the measurement to performing it and analyzing the data can be automated. The need for time consuming preparations and cleaning are removed with the disposable liquid tips.


Optical tensiometers are used in a great variety of industries and research areas, such as chemicalspharmaceuticalselectronicsfoodsenergypaper and packaging. Attension Theta Flex can be used for convenient and precise studies of:

  • Wettability
  • Adhesion
  • Homogeneity
  • Surface roughness
  • Spreading
  • Cleanliness
  • Printability
  • Adsorption
  • Emulsion and foam stability


Attension Theta Flex can perform a complete range of measurements including:

  • Static contact angle with the sessile drop, captive bubble and meniscus methods
  • Dynamic contact angle with the tilted drop and sessile drop methods
  • Surface free energy with the sessile drop, captive bubble and meniscus methods
  • Surface- and interfacial tension with the pendant drop and reverse pendant drop methods
  • Roughness-corrected contact angle and 3D surface roughness with the Fringe projection phase shifting method
  • Interfacial dilatational rheology with the pulsating drop method

OneAttension software

OneAttension features an intuitive user interface, live analysis and configurable user groups and accounts. In-depth analysis of your results takes a few seconds and data can easily be exported.

Modules and accessories

Attension Theta Flex enables you to choose the level of automation and the advanced functionalities that you need for your applications. With the modular design and an extensive range of modules and accessories you have room to upgrade or change the instrument as your needs evolve.

Attension Theta Flex: one instrument for all your measurement needs.

For more information or to request a quote, please contact us.

Thermo Fisher Scientific -Free webinar: Thursday, March 28, 2019

Thermo Fisher Scientific

This new webinar on 3D printing explains how it can be used competitively in applications such as aviation, automotive and medical devices.

Companies are turning to 3D printing for the freedom it offers in design, to lower product development costs and to make lighter-weight products. In medical applications, they’re also using it to increase patient comfort.

Yet certain industries such as aerospace and medical devices have stringent requirements that require new high-performance polymers. Marilys Blanchy R&D Project Manager at Rescoll (Société de Recherche) presents two case studies using high-performance compounds to outline strategies for formulation, extrusion, 3D printing and characterization. 

Promotion – Process 11/Mini Jet.


Thermo Scientific provides materials characterization solutions that analyze and measure viscosity, elasticity, processability and temperature-related mechanical changes in plastics, food, cosmetics, pharmaceuticals and coatings, chemical or petrochemical products and a wide variety of liquids or solids.

The company extends the capabilities of rheology with hyphenated techniques that provide molecular and microscopic information about a range of materials.
Products include lab-scale extruders and mixers, mini-injection molders, compounders, rheometers and viscometers to fully characterize materials.

Priding itself on providing innovative analytical instruments, lab equipment and specialty diagnostics, Thermo Scientifics’ products provide rapid and accurate results for customers in research, clinical and applied markets.


Spectra Research Corporation is excited to announce the release of CELLCYTE X, a live cell imaging microscope, by SRC supplier Cellink, one of the leading 3D bioprinting companies in the world. CELLCYTE X complements Cellink’s impressive bioprinting portfolio.



CELLCYTE X, a live cell imaging microscope


The future of live cell imaging

Details matter in live-cell imaging. That’s why Cellink designed a platform to provide the maximum insight scientists need to monitor every experiment. Cellink’s goal is to eliminate the obstacles and variables in cell monitoring – so you can focus on the results.

Cellink has reinvented microscopy by developing an insightful and user-friendly system that’s specifically made for the cell biology connoisseurs around the world. CELLCYTE X is the next-generation cell imaging platform designed to optimize data collection, analysis, and cell culturing processes. CELLCYTE X leverages the full power of Cellink’s DNA Cloud-based software to deliver continuous insight into your cells, enabling high-impact observation without the risk of disturbing an experiment. Who doesn’t want to know how their cells are doing from the comfort of their desk?

How CELLCYTE X works 

CELLCYTE X becomes a seamless component of any lab space, infusing your natural workflow with smooth usability and power results. 

  • Insert your sample.
  • Tell the Cellink software your study’s parameters.
  • Press Go.

CELLCYTE X is remarkably easy to use—helping keep your cells happy!


Just like that, CELLCYTE X begins automatically measuring cell health, movement and function to give you continuous and insight-packed analysis. While hardware-imposed storage limits hamper other analytical tools, CELLCYTE X harnesses the full power of Cellink’s Cloud-based algorithms to provide you the details when they matter most. 

Thanks to its compact design, CELLYTE X has a small footprint. Despite that, it has a six-microplate capacity, allowing it to be used by several researchers simultaneously—enhancing the efficiency of your lab and taking your research to a new level.