December 2020 Edition

New Technology

Introducing the DriveAFM high-performance atomic force microscope system

The DriveAFM, Nanosurf‘s new flagship instrument, utilizes the latest technology to deliver stable, high-performance performance. It was designed to fulfill the needs of top-notch research, today and in the future.

Sphere Fluidics lab image

New Product Line – Sphere Fluidics

SRC is pleased to announce its new product line from Sphere Fluidics—novel single cell analysis systems for the rapid screening and characterisation of single cells. Sphere’s patented picodroplet technology is designed to increase the chances of finding that rare molecule or cell that can lead to a life-changing medicine.

[Webinar Series]

Recordings are available online

at our resource centre – check them out!

  • Rokit for free webinar regarding cellular physiology of cancer cells in 3D
  • Sensofar Applications: Archeology & Paleontology Webinar
  • The Analytical Power of Correlative Raman Imaging: New Developments, Tools and Applications
  • Application of Atomic Force Microscopy in Virology Research by Asylum Research
  • Apium 3D Printing Application Webinar

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SRC Partners with Sphere Fluidics

SRC is pleased to announce that we have signed an agreement with Sphere Fluidics, an established UK life sciences tools company, giving SRC the exclusive right to sell Sphere Fluidics products in Canada. Spun out from the University of Cambridge, Sphere Fluidics has won over 50 international business and innovation awards—and now has exclusive agreements with 11 distributors across the world.

Sphere’s impressive array of patented products – biochips and specialist chemicals –currently assist hundreds of customers globally with their research. Sphere has a range of novel single cell encapsulation instruments and consumables that perform high-throughput singe cell (and molecule) analysis. 


Sphere’s main platform, Cyto-Mine®, is the next generation single cell analysis system for antibody discovery and cell line development. Current processes for finding novel antibody targets or developing stable cell lines are time consuming and inefficient. Cyto-Mine® allows you to accelerate, automate and simplify your antibody discovery and cell line development workflows.

Within several hours, it can automatically screen tens of millions of single cells in miniaturised aqueous picoliter compartments called picodroplets. The picodroplets are assayed for single cells that secrete valuable proteins (e.g. antibodies) and imaged (for monoclonality assurance) during subsequent dispensing of “hits”. Cyto-Mine® is enabling, increases throughput and reduces costs and time for biopharmaceutical discovery and development. 

 Sphere Fluidics 1

Sphere Fluidics

Picodroplet Single Cell Assay and Isolation System 

Sphere Fluidics research instruments are designed to assist you in finding highly valuable and rare biological variants among vast cell populations. By increasing speed and reducing cost, their picodroplet technology can help you save resources while boosting your chances of success.

Sphere Fluidics currently has two research instruments that enable you to generate, sort, and retrieve picodroplets for a range of applications. These are the Picodroplet Single Cell Encapsulation System and the Picodroplet Single Cell Assay and Isolation System. Both are compatible with their range of microfluidic specialist chemicals and biochips, as well as other standard and custom biochips from other sources.


ESI-Mine™ is a label-free platform for high-throughput, miniaturised electrospray injection mass spectrometry (ESI-MS). It can test up to 200,000 biomolecular samples (e.g. peptides, enzymes, antibodies, metabolites and small molecules) per day in miniaturized volumes of 500-700pL (picodroplets) facilitating more efficient screening and analysis in bioproduction or synthetic biology processes.

Applying this novel approach, researchers can create a large library of picodroplets containing microorganisms producing proteins or small molecules of interest for analysis. One major drawback of using MS in analysis is that samples are usually destroyed and cannot be retrieved. To overcome this total sample destruction by ESI-MS, Sphere has developed a unique microfluidics workflow where picodroplets are split into two replicate streams with identical clones, one stream is analyzed by ESI‐MS, and the second stream is subsequently ‘held’ and only those ‘hit’ daughter picodroplets sorted based on the result of the MS analysis.

Sphere Fluidics

Cyto-Cellect™ Human IgGκ Detection Kit

Sphere Fluidics’ Cyto-Cellect™ Human IgGκ Detection Kit, in combination with the Cyto-Mine® Single Cell Analysis System, offers a sensitive and robust assay ideal for streamlining cell isolation and titer determination. When picodroplets are formed during the Cyto-Mine® workflow, the Human IgGκ Detection probes are co-encapsulated with the cells to enable the detection of secreted IgG. The Cyto-Cellect™ Human IgGκ Detection Kit is a simple FRET assay that detects the presence of IgG with kappa light chain within picodroplets immediately after secretion from encapsulated cells. 

Sphere Fluidics customers

Sphere has an impressive list of customers in North America and around the globe who use their products and have published data at conferences or in scientific papers on their instruments. These include Janssen (US), GSK (UK and Spain), Merck (Germany), UCB (Belgium), Manchester University (UK) and Texas A&M (US).


Click here to contact SRC to learn more about Sphere Fluidics and their products.


Using contact angle measurements to study and QC surface treatments and coatings with Biolin Scientific

Biolin Scientific Webinar

Surface wettability and adhesion are vital phenomena in a variety of industries ranging from coatings industry to pharmaceutical and biomaterial industry. A simple and efficient contact angle measurement is often used for characterizing the water repellency and other properties such as how successful a surface treatment has been. In this webinar, we will go through the background and significance of different contact angles: where do they originate from, why are they important and how they can be measured in practice. We will give examples of situations where different kind of contact angle measurements are effective in characterizing the water repellency of a surface.

Upcoming Biolin Scientific Webinar


Join Spectra Research & Rokit for free webinar regarding cellular physiology of cancer cells in 3D

The cancer world isn’t flat: why cancer researchers adopt 3-D bioprinting

webinar regarding cellular physiology

The growing push for 3-D tissue models is limited by challenges in automated handling, processing and scalability of the technology to various types of materials and high-throughput applications. To meet these challenges, ROKIT Healthcare has developed all-in-one bioprinting platforms and human-cell derived ECM bioinks that allow researchers to biologically mimic the formation of complex, heterogeneous 3-D structures and to scale the technology to high-throughput applications. This webinar will focus on the platform’s usage in cancer biology. It will discuss evidence for 3-D bioprinting capturing altered proliferation and cell morphology profiles, revealing more realistic drug responses, and mimicking vascularized tumor microenvironments – to suggest why bioprinting of cancer cells is a scientifically rigorous method to generate physiologically relevant cancer models for preclinical screening and testing, as well as for new therapy research. You will learn about:
– Key advantages of 3D bioprinting over other techniques
– Five alterations in cellular physiology of cancer cells in 3D vs. 2D
– Evaluation of how 3D bioprinted tissues have altered proliferation and cell morphology
– Evaluation of how 3D bioprinted tissues reveal more realistic drug responses
– Evaluation of how 3D bioprinted tissues mimic complex tumor-immune microenvironments
– Built-in cell incubator, diverse material use, and high-throughput capabilities of ROKIT Healthcare’s all-in-one bioprinting platform Dr. INVIVO 4D6

photo of Dr. Sanjay Gupta

Dr. Sanjay Gupta

Professor & Research Director

Dr. Sanjay Gupta is a Professor & Research Director and holds Carter Kissell Endowed Chair in Urologic Oncology in the Department of Urology at Case Western Reserve University and The Urology Institute at the University Hospitals Case Medical Center. Dr. Gupta’s research focuses on understanding the risk factors and mechanisms of prostatic and bladder diseases, develop appropriate biomarkers for early detection and prognosis, identify novel targets to monitor the efficacy of various synthetic and natural agents and develop them as chemo preventatives/therapeutics Dr. Gupta has authored some 150 publications, including book chapters, research articles and reviews, and has spoken at several occasions in cancer prevention symposium, seminars and meetings. He has been serving in various study sections at National Cancer Institute (NCI) and Department of Defense (DOD), and other councils around the globe.

Madhuri Dey

Madhuri Dey

Ph.D Candidate @Ibrahim Ozbolat Lab – Penn State University
Da-Yae Lee

Da-Yae Lee

Senior Bio-Consultant @ROKIT Healthcare


Sensofar presents applications for Archeology & Paleontology!

Sensofar presents applications

Sensofar Applications: Archeology & Paleontology

Wednesday October 28, 2020
11:00 AM – 12:00 PM EDT


How can an optical profiler help to discover the diets of extinct species? And how did our ancient ancestors use tools in the Stone Age? These and other questions will be answered during this session, which we will be covering the Sensofar solutions for archaeology, paleontology and related fields of science.
Several applications will be presented such as the use of scale-sensitive fractal analysis in microwear studies, showing the advantages of our 3-in-1 technology. We want to show you how we helped make this amazing science easier, faster and more reliable.

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David Paez
Sensofar Metrology

Received bachelor’s degree in Engineering Physics at Polytechnic University of Catalonia (UPC) and MSc in Nanoscience and Nanotechnology at University of Barcelona (UB). As a Sales Specialist, I’ve helped customers all around the world to choose Sensofar’s systems, no matter the field they are in. Some of my duties are to communicate Sensofar’s knowledge about optical metrology and train our customers on how to extract all the potential from our 4-in-1 technology equipment.


Oxford Instruments Magnetic Resonance Webinar: Low-field NMR of polymer materials: An introduction to characterizing multicomponent polymer systems

New Webinar: Low-field NMR of polymer materials

Are you struggling with costly and destructive polymer characterization methods? Don’t miss the chance to learn how low cost, high accuracy polymer characterization can be achieved with Nuclear Magnetic Resonance (NMR) spectroscopy. Discover how benchtop NMR spectroscopy characterizes polymer composition, microstructure, physical properties and monitors synthesis reactions.   

Join Dr Bryan S. Beckingham, Assistant Professor, Auburn University and Marcel Lachenmann, Senior Applications Scientist, Oxford Instruments for our webinar hosted by Select Science. 

During the webinar you will learn about: 

  • How benchtop NMR accelerates polymer R&D
  • The role of NMR in polymer manufacturing
  • The impact and choice of NMR instrumental parameters
  • The influence of polymer sample properties

Please forward this email to your contacts, colleagues, and friends who may be interested in this webinar.

Date: Thursday, September 24

Time: 16:00 BST / 11:00 EDT / 08:00 PDT / 17:00 CEST

Dr Bryan S. Beckingham Dr Bryan S. Beckingham

Assistant Professor at

Auburn University

Marcel Lachenmann Marcel Lachenmann

Senior Applications Scientist at Oxford Instruments


Welcome to ROKIT Organ Regeneration Travel Tuesday!

ROKIT Healthcare invites you to webinars every Tuesday, sharing knowledge on organ regeneration applications, recent trends in biomedical research fields. ROKIT opens up space for you to join this series webinar, so we all can enjoy the entire journey with experts in similar fields.

Please mark on your calendar the following schedules!

To join the webinar, please RSVP at ROKIT’s website.

After the RSVP, join us at the right time via the Zoom link below:

ROKIT Organ Regeneration

ROKIT Healthcare Travel Tuesday Webinars] 

Here is your boarding pass to ROKIT Travel Tuesday series webinars! Please choose the most convenient time for you to board. We look forward to having you there! See you!

About Spectra Research Corporation (SRC)

SRC is Canada’s premier source for innovative high-quality scientific products and laboratory services to industrial and scientific markets in Canada. Through continuous improvement and quality practices, SRC provides clients with exceptional laboratory services and support. An ISO9001-registered company, SRC delivers technical expertise and industry knowledge for all of the products represented.


The Analytical Power of Correlative Raman Imaging: New Developments, Tools and Applications

Analytical Power


The Analytical Power of Correlative Raman Imaging: New Developments, Tools and Applications

Confocal Raman imaging is a powerful, versatile and increasingly common microscopy technique, capable of quickly identifying the molecules in a sample and visualizing their physical distribution three-dimensionally. This nondestructive and label-free chemical imaging method has enormous potential for researchers in many fields of application.

This webinar will introduce the fundamental principles of Raman microscopy and it will detail the associated hardware and software. Our speakers will describe several of its variations providing relevant application examples. Correlative microscopy will then be introduced, and details of Raman-AFM and Raman-SEM (RISE) microscopy solutions will be presented.

Key Learning Objectives
During this webinar, the speakers will present:

  • What Raman microscopy is, along with an introduction to its operational principles and hardware considerations.
  • Possibilities and new tools for Raman investigations including several application examples from various fields.
  • How correlative microscopy can provide a more complete understanding of a sample than techniques in isolation.

Sep 10, 2020 11:00 AM in Eastern Time (US and Canada)


photo of Dr. Miriam Böhmle
Dr. Miriam Böhmler
Senior Applications Scientist @WITec GmbH
Dr, Miriam Böhmler is a Senior Applications Scientist at WITec GmbH in Ulm, Germany. She possesses wide-ranging expertise in Raman imaging and spectroscopy, near-field and super-resolution optical technologies such as tip-enhanced Raman spectroscopy, and nano-FTIR spectroscopy.
photo of Dr. Ute Schmidt
Dr. Ute Schmidt
Applications Manager @WITec
Dr. Ute Schmidt is an Applications Manager at WITec. She studied physics at the Babes Bolyai University in Cluj-Napoca, Romania, and obtained her PhD from the University of Karlsruhe, Germany. Through her work with in-situ scanning tunneling microscopy, Atomic Force Microscopy and SEM, Schmidt is an expert for correlative imaging techniques.


Correlative Raman Imaging

The Next Tool in Surface Metrology Introducing the S wide

SRC is pleased to introduce Sensofar Metrology’s new metrology tool for wide areas—the S wide. The S wide is a dedicated system designed to rapidly measure large sample areas up to 300 x 300 mm. It provides all the benefits of a digital microscope integrated into a high-resolution measuring instrument. On top of that, with single button acquisition, it is extremely easy to use.

S wide

Large-area 3D optical system


The S wide is a large-area 3D optical system providing solutions in the following fields:

  • Advanced manufacturing
  • Archaeology and paleontology
  • Consumer electronics
  • Medical devices
  • Molding
  • Optics
  • Watches

S wide features

  • Sub-micron height repeatability over entire extended area
  • One shot height measurement up to 40 mm without Z scanning
  • Bi-telecentric lenses with very low field distortion providing accurate metrology
  • Form deviation from 3D CAD models, providing the geometric difference and tolerance measurement


S wide

ISO standards


Every S wide is manufactured to deliver accurate and traceable measurements. Systems are calibrated using traceable standards according to ISO 25178 and VDI 2634-2. 

Request a quote

Click here to request a quote on a Sensofar Group product.

About Sensofar Metrology

Sensofar Metrology is a member of the Sensofar Group, headquartered near Barcelona, a technology and innovation hub. Sensofar Metrology’s mission is to develop, manufacture and market high-end 3D surface metrology instruments. They also provide consultancy within the field of metrology, and pursue a philosophy of guaranteeing advanced techniques, high quality and customer service.


FREE WEBINAR FROM ASYLUM RESEARCH on Application of Atomic Force Microscopy in Virology Research


Wednesday August 12, 2020
12:00 PM – 1:00 PM EDT

Atomic Force Microscopy has found broad use in the biological sciences. It is an indispensable tool for both high resolution imaging of individual molecules, cells, tissues, viruses and biomaterials. Since AFM is also relatively non-destructive and requires minimal sample preparation (i.e. no coating/fixing/labeling), it is ideally suited to visualize
dynamic biomolecular processes at the nanoscale.
We will present relevant data to illustrate the potential of Asylum Research’s AFMs in virus research.


Sophia Hohlbauch, Senior Biological Applications Scientist @Asylum Research
Sophia Hohlbauch has over 20 years of AFM experience specializing in the life sciences. She is currently a Senior Biological Applications Scientist at Asylum Research and previously held a similar position at Digital Instruments/Veeco. She has presented on AFM topics at numerous biology and AFM meetings worldwide. Her background is biology, receiving Bachelor’s and Master’s degrees in Marine Biology from the University of California, Santa Barbara.