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Edition 2 | April 2016
Welcome to the latest edition of Materials Characterization in Focus, a quarterly eNewsletter which brings you the latest information and events for our Material Characterization, Spectroscopy, Surface Analysis and Microanalysis solutions.
Products » Seminars, Workshops, & Training » Webinars » Trade Shows & Conferences »
NEW Pharma 16 Twin-Screw Extruder
The 2-in-1 Extruder
Now you can quickly switch from hot melt extrusion (HME) to wet granulation (TSG) with the new Thermo Scientific™ Pharma 16 Twin-screw Extruder for solid drug dosage manufacturing. Our scientific method can help you scale-up your API/excipient formulation with less effort and reduce the use of expensive API.

The Pharma 16 extruder is our mid-sized extruder, and is geometrically similar to our small- and large-sized extruders. This means minimal time is required to optimize critical equipment parameters going from the formulation lab to manufacturing.

Whether you are developing transdermal patches, implants or tablets, you can shorten your time to market using a continuous process for HME or TSG. Using the new Pharma 16 twin-screw extruder, you can achieve your drug development goals with these unique features:

  • Switch from an HME to a TSG process using one extruder
  • Effortlessly integrate upstream and downstream process equipment
    (e.g., feeders, chill rolls, pelletizers, dryers) with plug-and-play hardware and software
  • Quickly disassemble parts for easy cleaning and validation
  • Control process parameters with an intuitive touch-screen interface
  • Scale up your continuous process with less optimization time than a batch process
Learn more about the Thermo Scientific Pharma 16 Twin-screw Extruder.

New HAAKE Viscotester IQ Air-Bearing Rheometer
Providing Enhanced Measurement Capabilities and Greater Flexibility

The new Thermo Scientific™ HAAKE™ Viscotester iQ Air rheometer is portable, easy to use and provides improved performance combined with an extended measurement range. Scientists from development laboratories, industrial QA/QC and research seeking to increase work flow efficiency and reduce operator errors, can now rely on a portable, versatile and modular air-bearing oscillation rheometer.

The HAAKE Viscotester iQ Air rheometer sets new standards for footprint size, ease of use and usability. It features a modular design so users can quickly exchange measuring devices to accommodate a variety of sample viscosities and measurement requirements. This is not only ideal for today’s challenging industrial applications, but also will enable labs to expand capabilities as their needs change.

For more information on the newest member of our rheometric family, please visit


New DXR2 Family of Raman Instruments
For Application in Materials Science, Life
Science, and Pharmaceutical Science
We are proud to introduce the new DXR2 family of Raman instruments. These include the Thermo Scientific™ DXR™2xi Raman imaging microscope, the Thermo Scientific™ DXR™2 Raman microscope, and the Thermo Scientific™ DXR™2 SmartRaman spectrometer.

The DXR2 family of Raman instruments assists scientists in Materials Science, Life Science, and Pharmaceutical Science, and now offers the following new features:


  • Material Science – the addition of polarized Raman spectroscopy in our microscopes enables the detection of molecular orientation, crystallinity, and other morphological traits found in samples
  • Life Science – we have added a number of data collection modes to help overcome challenges with fluorescing or low-scattering biological samples
  • Pharmaceutical Science – new qualification and data integrity tools will enable compliance with recommendations from standards bodies
Please visit our web site for further information on the new DXR2 family of Raman instruments.

New Nicolet iS5N FT-NIR Spectrometer
Near-infrared Solutions to Fit Your QC Lab and Your Budget

Bring near infrared (NIR) capabilities to the lab with the new Thermo Scientific™ Nicolet™ iS™5N FT-NIR spectrometer. Based on the rugged Nicolet iS5 FT-IR spectrometer and powerful Thermo Scientific™ OMNIC™ software, the Nicolet iS5N offers minimum hassle and maximum confidence in your results. Get rapid, accurate results to help you make critical decisions to ensure product quality.

Learn more about Nicolet iS5N FT-NIR spectrometer.

Read New Application Notes on Polarized Raman Spectroscopy

Two new application notes supporting Polarized Raman spectroscopy are now available. “Fundamentals of Raman Polarization Microscopy” is a useful reference piece describing the general theory and application of Raman polarization. “Observing Molecular Orientation in Isotactic Polypropylene Films with Polarized Raman Spectroscopy” is an application note to show how polarized Raman spectroscopy can further understanding of polymer materials, specifically under stretching conditions.

Download Fundamentals of Raman Polarization Microscopy.

Download Observing Molecular Orientation in Isotactic Polypropylene Films with Polarized Raman Spectroscopy.


Hot Melt Extrusion (HME) Webcast

Continuous Manufacturing of Pharmaceuticals:
Scale-up of a Hot Melt Extrusion Process

14 April 2016
8:00PDT | 11:00 EDT | 16:00 BST | 17:00 CEST

Join us for a live, online seminar. In this webcast, experts will discuss residence time, mechanical-energy consumption, and other critical parameters to manage an HME continuous process. They will also examine a scientific approach to process scale-up.

Key Learning Objectives:

  • How HME parameters affect final solid dosage forms
  • How to scale-up a continuous process from research to production, while minimizing process optimization and improving API solubility
  • How to optimize parameters to meet product quality
Register now.

Spectroscopic Solutions Workshops 2016

This free, interactive, skills-building workshop series is taking place now in cities across North America. Join us for these dynamic workshops designed to improve your spectroscopy knowledge and skills. See the latest Thermo Scientific™ instrumentation in action and have your questions answered live.

Reserve your place today!
Advanced Material Science Research Webinar Series

Introduction to Polarized Raman Microscopy
7 April 2016
Session 1:
9:00 EDT | 13:00 GMT
Session 2:
12:00 EDT | 16:00 GMT

Polarized Raman spectroscopy is an essential tool for investigating and confirming molecular structure and sample orientation. Molecular orientation can be determined through the analysis of samples such as crystals, stretched films or fibers, microstructure materials and other materials. Molecular orientation can have a direct impact on physical properties such as strength, flexibility or conductivity of these materials.

Learn the fundamentals of polarized Raman microscopy, measurement and meaning of depolarization ratio, and the use of polarized Raman spectroscopy for assessing sample orientation.

Register today!

Register for the “Foundations to Futures” FTIR Webinar Series

Webinar 4: Materials Applications with a
Multi-Range FTIR Spectrometer

27 April 2016
Session 1: 9:00 EDT | 13:00 GMT
Session 2: 11:00 EDT | 15:00 GMT

If you are in the materials, polymers, pharmaceutical or optics industries, you may benefit from spectral range coverage beyond the conventional mid-IR. However, in the past, changing over your FTIR instrument may have required time-consuming manual intervention and subsequent re-stabilization. Now, even novice users can change their instrument configuration with the automated Thermo Scientific™ Nicolet™ iS™50 FTIR spectrometer – for easy access to valuable information in the far-IR, near-IR, or even into the UV-Visible range.

Attend this webinar and learn more about applications available in the extended spectral range.

To learn more information about our future webinars, please visit our web site where you will find a complete schedule.

Upcoming and Recorded Webinars
We have a range of upcoming webinars and also recorded webinars for you to watch at your convenience.


10th World Meeting on Pharmaceutics, Biopharmaceutics, Pharmaceutical Technology
4-7 April 2016
Glasgow, UK

Booth 39

The 10th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology (PBP 2016) with the accompanying exhibition from ResearchPharm®, provides a cross-disciplinary platform for pharmaceutical scientists from industry, academia and regulatory bodies, working in the field of drug product development. The ResearchPharm exhibition will present the latest trends and products in the areas of pharmaceutical ingredients, development and processing equipment, analytical technologies, medicinal products, medical devices, contract manufacturing and recent publications.

On our booth we will be showcasing the Thermo Scientific™ Pharma 11 Twin-screw Extruder, as well promoting our spectroscopy product lines. We will also feature a poster presentation on granulation and drying in continuous processing.

For more information on our participation at this event please visit our web site.

10-13 May 2016
Munich, Germany

Booth B1-101

Analytica is the international trade fair for innovative laboratory technology, analysis and pioneering biotechnology. It covers the entire supply chain – not only for laboratories in industry, but also in the research and science sectors. Connect with us to see the latest innovative products and services, and discuss your analytical challenges with peers and our technical experts.

Featured Thermo Scientific™ products will include:

  • Thermo Scientific™ GENESYS™ 30 spectrophotometer
  • Thermo Scientific Nicolet iSN5 FT-IR Spectrometer
  • Thermo Scientific™ DXR™2xi Raman imaging microscope
  • Thermo Scientific HAAKE Viscotester iQ “Air” rheometer
  • Thermo Scientific™ Nicolet™ iS™50 FT-IR Spectrometer
  • Thermo Scientific HAAKE MARS 40 rheometer
For more information, please visit our web site.

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