Technologies

• Raman spectroscopy offers a non-invasive optical approach that preserves sample integrity.
• Simultaneous measurement of multiple molecular constituents in biological samples saves time and resources.
• Eliminates the need for sample staining or labeling.
• Provides high specificity, aiding in the discovery and validation of early disease markers.
• High-resolution Raman images offer comprehensive biomolecular and morphology information.

• Collect sequential Raman and AFM measurements
• Supports Dimension Icon, Dimension FastScan and Dimension Edge
• No need to move samples between systems
• Non-invasive coupling enables each instrument to be used independently without compromising performance
• Supports Raman imaging on the AFM
• Compatible with a comprehensive range of AFM modes including PeakForce TUNA™ for electrical characterization and PeakForce QNM® for quantitative nanomechanical mapping

The S mart 2 is the only autonomous areal confocal profilometer available on the market, and it is incredibly easy to install as it requires only two single connections (ethernet cable and a power supply). Its narrow width allows the integrable head to be installed in even the most difficult of zones, while its easy integration is enabled by the presence of all the electronics, including the computing power, inside the head. Furthermore, its high–efficiency passive cooling system ensures that the system is always ready to work.

• The SA-9600 series of surface area analyzers offers fast, convenient, and cost-effective measurements of surface area on a wide range of materials.
• It allows for ultra-fast single or multi-point surface area measurements with easy operation.
• The analyzers utilize the flowing gas method to acquire gas adsorption and desorption data, which is then used to calculate total surface area using the BET method.
• The flowing gas method is particularly advantageous in single-point mode, enabling up to thirty sample analyses per hour.
• The patented SA-9600 technology enables routine total surface area determination in as little as two to six minutes.
• The SA-9603 models have three stations for simultaneous surface area measurements.

• NL-UHV enables the generation and deposition of nanoparticles in an Ultra-High vacuum to create functionalized surfaces on samples.
• The properties of the nanoparticle coatings can be precisely controlled, including size, composition, and structure, allowing for tailored properties.
• NL-UHV instruments allow the direct deposition of ultra-pure nanoparticles on a wide range of substrates and materials.
• The film density can be adjusted, and the coating adheres well to the sample surface.
• Available in different configurations, including single 1″ and 2″ sources, as well as the triple 1″ source NL-DX3, which enables the deposition of up to three materials individually or as alloys.
• The NL-QMS mass filter offers advanced control over nanoparticle deposition, allowing the scanning or filtering of nanoparticles by mass or diameter in real-time.
• The NL-QMS is operated through user-friendly WindowsTM software, providing intuitive control over the deposition process.

• The ViewSizer 3000 is an advanced analyzer for exosomes, viruses, and nanoparticles.
• It uses multiple lasers for accurate and detailed analysis of particles in a sample.
• The device simultaneously measures particle size and concentration across a wide range of sizes.
• It adjusts laser power to avoid saturation or weak scattering, ensuring precise data.
• The ViewSizer 3000 is designed for easy cleaning to prevent cross-contamination.
• It provides accurate and sensitive analysis without the risk of cross-contamination.

• High performance portable fibre coupled Raman system
• High spatial resolution x/y <1 µm, z <2 µm
• Live white light sample viewing for accurate sample targeting
• Motorised x/y/z stack that enables accurate objective positioning for single point or mapping purposes
• Work with objective lens pointing downwards or horizontally

Y-Type Diamond Interaction Chamber (DIXC) is used to produce uniform nanoparticles in a high pressure homogenizer. The fixed geometry within the Y-Type DIXC is intended to create a uniform processing profile so that all materials will be processed with equal disruptive forces. Single-slotted interaction chambers have a single microchannel and are ideal choices for small batch research, while the multi-slotted interaction chamber comprises multiple microchannels in parallel, which can be used at industrial scales, by increasing the flow rate through the DIXC but with equal processing forces.

Z-Type Diamond Interaction Chamber (DIXC) is used to produce uniform nanoparticles in a high-pressure homogenizer. The fixed geometry within the Z-Type DIXC is intended to create a uniform processing profile so that all materials will be processed with equal disruptive forces. Single-slotted interaction chambers have a single microchannel and are ideal choices for small batch research, while the multi-slotted interaction chamber comprises multiple microchannels in parallel, which can be used at industrial scales, by increasing the flow rate through the DIXC but with equal processing forces.

Diamond Interaction Chamber (DIXC) is used to produce uniform nanoparticles in a high-pressure homogenizer. The fixed geometry within the DIXC is intended to create a uniform processing profile so that all materials will be processed with equal disruptive forces. Single-slotted interaction chambers have a single microchannel and are ideal choices for small batch research, while the multi-slotted interaction chamber comprises multiple microchannels in parallel, which can be used at industrial scales, by increasing the flow rate through the DIXC but with equal processing forces.

Mixing Diamond Interaction Chamber (DIXC) is a chamber specially designed for mixing and homogenizing the sample fluids from two or more inlet ports. The multiple streams will mix homogenously at the diamond mixing chamber where the fluids pass through the fixed micro-channels and experience high shears and strong impacts.

The HandExtruder is a manually powered extruder designed for the formulation of 0.25mL-2.0mL liposome and lipopolyplex with small samples. The sample is passed back through the membrane by being pushed back and forth between two syringes. Homogeneous samples can be produced quickly and easily in minutes; typically 5-10 passes are sufficient to produce a sample with uniform liposome size. The HandExtruder offers minimal dead-volume, is easy to clean and is suitable for sterilization. Temperature control is available

Genizer Multi Online Liposome Extruders System can be connected with a sanitary pump or high pressure homogenizer and are temperature-controlled, from pilot testing to manufacturing production of pharmaceutical liposomes such as anti-cancer drugs. Homogenous samples can be produced quickly and easily in minutes; typically 3-5 passes are sufficient to produce a sample with uniform liposome size. The Genizer Multi Online Liposome Extruders System is designed to generate homogeneous unilamellar liposomes and lipopolyplex. Extrusion is a one-step procedure that produces liposomes by forcing lipid suspensions of drug, protein or gene through track-etched filters of defined pore size. The Multi Online Extruders System offers minimal dead volume, is easy to clean, suitable for sterilization and compliant with FDA and GMP sanitary standards in pharmaceuticals.

The Genizer Jacketed Liposome Extruders is compressed air-driven and temperature-controlled, from testing to manufacturing production of liposome and lipopolyplex, for drug and gene delivery. Homogeneous samples can be produced quickly and easily in minutes; typically 5-10 passes are sufficient to produce a sample with uniform liposome size. Genizer Jacketed Liposome Extruders are designed to generate homogeneous unilamellar liposomes and Lipopolyplex. Extrusion is a one-step procedure that produces liposomes by forcing lipid suspensions of drug, protein or gene through track-etched filters of defined pore size. The process is relatively gentle, exposing the formulation to moderate pressures up to 500 psi at controlled temperatures. The Genizer Jacketed Extruder offers virtually no dead-volume, is easy to clean, suitable for sterilization and in compliance with FDA and GMP sanitary standards in pharmaceuticals.

• Form deviation from 3D CAD models
• Calibration of surface texture measuring instruments
• Sub-micron height repeatability over entire extended area
• One shot height measurement up to 40 mm without Z scanning
• Bi-telecentric lenses with very low field distortion providing accurate metrology