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Nanosurf FluidFM® probe microscopy

Market leading experience in FluidFM for AFM

Highly accurate pressure, force, and position control with optical sample access
Different FluidFM® probes: hollow cantilevers designed for specific applications
Pioneering research within reach

Introducing the Nanosurf FluidFM® probe microscopy

The established microfluidic tool for nanomanipulation and single-cell biology

FluidFM probe microscopy (FPM) combines the force sensitivity and positional accuracy of an AFM with FluidFM technology by Cytosurge to allow a whole range of exciting applications in single-cell biology and nanoscience.

Nanosurf has the longest experience providing AFM systems with the FluidFM^® add-on, as Cytosurge’s initial cooperation partner for this innovative technology – the FlexAFM with FluidFM^® system was launched in 2013. FluidFM add-ons are available for the FlexAFM and CoreAFM platforms and a unique integrated FPM solution on the FlexAFM.

Key Features

Highly accurate pressure, force, and position control with optical sample access

Fully integrated system with user-friendly FluidFM^® ARYA operator software
FluidFM® microfluidics control system
Compatible with major inverted microscope brands

Different FluidFM^® probes: hollow cantilevers designed for specific applications

FluidFM® micropipettes: tipless cantilevers with opening at the cantilever end
FluidFM® nanopipettes: cantilevers with opening at the tip apex
FluidFM® rapid prototyping probes: cantilevers with closed pyramidal tips, ready for FIB milling

Pioneering research within reach

A tool to conduct original research at the frontiers of science

An integrated solution with optical, force, and fluidic control

Optical cell selection by fluorescence properties (left image). The cantilever was gently placed on the cell under force control and trypsin administration was monitored from a co-deposited fluorescence dye (blue). After release, the cell was picked up with the same cantilever and isolated from the rest by placing it in a separate well, sorted by fluorescence (right image; adapted from Lab Chip (2014) 14, 402‑414 with permission from The Royal Society of Chemistry). Data courtesy: O. Guilaume-Gentil, ETH Zürich, Switzerland.

Key Benefits

Innovative and intuitive handling

With its touchscreen interface and predefined experimental workflows, e.g for single-cell injection and extraction or for bacterial and cell adhesion force measurements, the intuitive FluidFM ARYA operator software will guide you through each of your experiments step-by-step.

All FluidFM probes come in sterile blister packs and pre-mounted on plastic carrier clips. Each blister pack has a QR code that can be read with the QR code reader supplied with the Flex-FPM system to allow direct import of detailed cantilever information into the operator software.

Trust the Experts at Spectra Research Corporation

Spectra Research Corporation (SRC) offers a range of innovative high-quality scientific products and laboratory services to industrial and scientific markets throughout Canada.

Specifications

FluidFM specifications

Pressure system specifications
Pressure range	–800 to 1000 mbar
Pressure precision	better than 2.5% of full range
Min. output pressure step (< 0 mbar)	0.1% of max negative pressure range
Min. output pressure step (> 0 mbar)	0.1% of max positive pressure range
Power consumption	< 32 W

Datasheet

Nanosurf FluidFM® probe microscopy

Market leading experience in FluidFM for AFM

Introducing the Nanosurf FluidFM® probe microscopy