Pharma 11 Twin -screw Extruder

Perform material- and labor-effective extrusion with Thermo Scientific™ Pharma 11 Twin-screw Extruder, which requires only a small amount of active pharmaceutical ingredient, operating at throughput levels as low as 20g/h.The parallel 11mm twin screws and compact design of the Pharma 11 Twin-screw Extruder is fully scalable with the Thermo Scientific stand-alone pharmaceutical compounding systems. Together, you can obtain process relevant results or even perform small scale production.If you need a complete extrusion solution, a wide range of accessories are available for the Pharma 11 Twin-screw Extruder, including volumetric and gravimetric feeders, a conveyor belt and a pelletizer.

 

Product Description

The Pharma 11 Twin-screw Extruder Features:

  • Uses smaller material quantities for faster, cost-effective development
  • Converts easily from hot melt extrusion (HME) to twin screw granulation (TSG) applications
  • Operates at throughput ranges from 20g/h up to 2.5kg/h
  • Processing length: L/D ratio 40:1
  • Screw elements and barrel design scale geometrically across the all Thermo Scientific Pharma Extruders and allow easy process scale-up
  • Easy-to-operate with user-friendly, intuitive touch screen with integrated feeder control
  • Maximize lab space with small footprint machine
  • Perfect for glove box or isolator applications with removable touch screen
  • All material contact parts are easily removable
  • Documentation of extrusion parameters and suitable for process analytical technology (PAT)
  • GMP-compliant, full validation available: FAT, SAT, IQ/OQ

Catalog #

Description

 

Quantity 553-0020

Pharma 11 HME; 40:1, 1000rpm
Full specifications
Feed Zones Permanent liquid cooled feeding port
Max. Temperature 280°C
Heating Zones 7 x 5 L/D heat/cool zones, +1 heating zone for die
Width (Metric) 50cm
Height (Metric) 41cm
Pressure 100 bar, safety monitored
Screw Diameter (Metric) 11mm
Length (Metric) 90cm
Screw Type co-rotating parallel twin-screw
Speed Variable speed drive system 10 to 1000rpm
Material Pharma grade stainless steel Boehler M340
Temperature (Metric) Operating 10 °C to 280 °C (with appropriate cooling device)
Throughput 20 g/h up to 2.5kg/h
Description Pharma 11 HME; 40:1, 1000rpm
Diameter (Metric) 11mm
Max. Screw Speed 1000rpm
Max. Torque 6 Nm per shaft, constant torque, safety monitored
Item Description Pharma 11 HME; 40:1, 1000rpm
Weight (Metric) 55kg

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553-0138

Pharma 11 Controlled Cooling 40:1 (Bottom Barrel only)
Full specifications
Feed Zones Permanent liquid cooled feeding port
Heating Zones 553-0138
Width (Metric) 50 cm
Height (Metric) 41 cm
Pressure 100 bar, safety monitored
Length (Metric) 90 cm
Speed Variable speed drive system 10 to 1000rpm
Material Pharma grade stainless steel Boehler M340
Temperature (Metric) Operating 10 to 280 (with appropriate cooling device) °C
Description Pharma 11 Controlled Cooling 40:1 (Bottom Barrel only)
Voltage 230 V
Max. Torque 553-0138
Item Description Pharma 11 Controlled Cooling 40:1
Weight (Metric) 55 kg

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553-0400

Pharma 11 Volumetric Single Screw Feeder
Full specifications
Feed Zones Permanent liquid cooled feeding port
Heating Zones 553-0400
Width (Metric) 50 cm
Height (Metric) 41 cm
Pressure 100 bar
Length (Metric) 90 cm
Screw Type different screw types available
Speed Variable speed drive system 10 to 1000rpm
Material Pharma grade stainless steel Boehler M340
Temperature (Metric) Operating 10 to 280 (with appropriate cooling device) °C
Throughput depending on screw type and speed up to 4kg/h
Description Pharma 11 Volumetric Single Screw Feeder
Max. Screw Speed 120rpm
Voltage 230 V
Max. Torque 553-0400
Item Description Pharma 11 Volumetric Single Screw Feeder
Weight (Metric) 55 kg

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553-0610

Pharma 11 Varicut Pelletizer
Full specifications
Feed Zones Permanent liquid cooled feeding port
Heating Zones 553-0610
Width (Metric) 50 cm
Height (Metric) 41 cm
Pressure 553-0610
Length (Metric) 90 cm
Speed Variable speed drive system 10 to 1000rpm
Material Pharma grade stainless steel Boehler M340
Temperature (Metric) Operating 10 to 280 (with appropriate cooling device) °C
Description Pharma 11 Varicut Pelletizer
Voltage 230 V
Max. Torque 553-0610
Typical Output Pellet size between 0.5mm and 2.0mm in 0.5mm increments (depending on material)
Item Description Pharma 11 Varicut Pelletizer
Weight (Metric) 55 kg

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553-0600

Pharma 11 Air Cooled Conveyor
Full specifications
Feed Zones Permanent liquid cooled feeding port
Heating Zones 553-0600
Width (Metric) 50 cm
Height (Metric) 41 cm
Pressure 553-0600
Length (Metric) 90 cm
Speed Variable speed drive system 10 to 1000rpm
Material Pharma grade stainless steel Boehler M340
Temperature (Metric) Operating 10 to 280 (with appropriate cooling device) °C
Description Pharma 11 Air Cooled Conveyor
Voltage 230 V
Max. Torque 553-0600
Item Description Pharma 11 Air Cooled Conveyor
Weight (Metric) 55 kg

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