New Supplier Announcement

Cordouan

SRC is pleased to announce that we have concluded an agreement with Cordouan Technologies to be exclusive distributor in Canada of their VASCO KIN™ particle analyzer— a role we take on with great enthusiasm.

VASCO KIN™ 

The VASCO KIN™ is a Nanoparticle Size Analyzer. A new generation of time-resolved instruments for accurate kinetic analyses combined with an in situ and contactless remote optical head. It allows for real-time monitoring of nanoparticle synthesis, agglomeration or the stability of suspensions using Dynamic Light Scattering (DLS). With a single and continuous measurement, VASCO KIN™ gives access to all characterization data of a reaction (size distribution, scattered intensity, correlogramms, etc.).

 

VASCO KIN

Key features and benefits

  • Frequency stabilized laser and artefact-free Avalanche Photodiode (APD) detector
    → High measurement accuracy
    → Very low sample scattering
  • Embedded dedicated PC, including software correlation and complete and dedicated software NanoKin®
    → User-friendly interface
    → Photon-counts storage for time-resolved analysis and post-analysis
    → Full reports, including kinetic analysis
  • Enhanced mathematical models
    → Better reliability of results
    → 2D colormap of size distribution over time

Main specifications

  • Measurement principle: Optical fiber Dynamic Light Scattering (DLS)
  •  Measurement configuration: in situ / contactless remote probe
  • Particle size range: 0.5 nm  to 10 µm*
  • Concentration range: up to 40% wt*
  • Measurement time: from 2s up to 12 hours
  • Time resolution: down to 200 ms
  • Small footprint, no moving parts, and easy-to-integrate in harsh environments

About Cordouan Technologies

Cordouan Technologies is a French company specializing in advanced solutions for characterization (size, charge, etc.) of nanoparticles and nanomaterials. They develop, industrialize, manufacture and sell innovative instruments dedicated to academic research and industrial applications (process monitoring, quality control and R&D).

Cordouan Technologies’ unique product portfolio stems from patented and innovative technologies transferred from prestigious institutes, including Institut Français du Pétrole (IFPEN), Karlsruhe Institute of Technology (KIT) and Institut Charles Sadron (ICS).

 

Nanosurf webinars and live demonstrations

Nanosurf webinars

Nanosurf regularly holds webinars on topics of interest to our industry as well as live demonstrations of Nanosurf AFMs. All these events are free of charge and open to everyone. We hope to be able to provide you with an interesting learning opportunity during these times of restricted possibilities.

Introduction to the DriveAFM

On March 25, we are holding a webinar for everyone who is interested in learning more about the DriveAFM. Dr. Christian Bippes, the product manager for the DriveAFM, will be holding an in-depth presentation, and will be available for an extensive Q&A session.

During the presentation Christian will show several example measurements he has made in the past weeks, and explain how he was able to achieve these results using the DriveAFM, also touching on the technology enabling this astounding image quality.

March 25, 2021 | 09:00 CET (Zurich)

Register Now

March 25, 2021 | 18:00 CET (Zurich)

Register Now

HOPG topography recorded in static mode on 100 µm scanner

HOPG topography recorded in static mode on 100 µm scanner

 

3D topography of a grating structure with 390 nm deep trenches and an aspect ratio of ~2.2

3D topography of a grating structure with 390 nm deep trenches and an aspect ratio of of – 2.2

High-resolution topography image of double-stranded DNA (dsDNA) adsorbed to mica in buffer solution

High-resolution topography image of double-stranded DNA (dsDNA) adsorbed to mica in buffer solution

MFM images of a Shakti lattice

MFM images of a Shakti lattice

 

 

Conductive AFM on ITO

Conductive AFM on ITO

 

 

Cell-cell adhesion force studied with Flex-FPM

Cell-cell adhesion force studied with Flex-FPM

Cell-cell adhesion force studied with Flex-FPM

Nanosurf webinars 1.JPGNanosurf webinars

 

New Hire Announcement

Vlad Shuster

Vlad Shuster.jpg

SRC is pleased to announce the recent hiring of Vlad Shuster for the position of Account Manager—Ontario and the Atlantic Provinces, commencing March 8, 2021.

Vlad studied chemistry in Israel and Canada, obtaining a B. Sc. in Medicinal Chemistry (2002) and an M. Sc. in Polymer Chemistry from Bar-Ilan University (2004) and an M. Sc. in Chemistry from the University of Ottawa (2010).

Prior to joining SRC, Vlad has occupied different scientific and sales/business development roles at Johnson and Johnson (Omrix Biopharmaceuticals), Scintrextrace Corporation, Laser Distance Spectrometry, CEM Specialties/ABB Channel Partner and Thermo Fisher Scientific.

Vlad is a results-oriented, assertive and self-motivated individual with strong technical and commercial skills. He is poised for success in his new role at SRC and we are thrilled to have him join the ACA Group of Companies.

Contact Vlad at  Spectra Research Corporation

 

December 2020 Edition

New Technology

Introducing the DriveAFM high-performance atomic force microscope system

The DriveAFM, Nanosurf‘s new flagship instrument, utilizes the latest technology to deliver stable, high-performance performance. It was designed to fulfill the needs of top-notch research, today and in the future.

Sphere Fluidics lab image

New Product Line – Sphere Fluidics

SRC is pleased to announce its new product line from Sphere Fluidics—novel single cell analysis systems for the rapid screening and characterisation of single cells. Sphere’s patented picodroplet technology is designed to increase the chances of finding that rare molecule or cell that can lead to a life-changing medicine.

[Webinar Series]

Recordings are available online

at our resource centre – check them out!

  • Rokit for free webinar regarding cellular physiology of cancer cells in 3D
  • Sensofar Applications: Archeology & Paleontology Webinar
  • The Analytical Power of Correlative Raman Imaging: New Developments, Tools and Applications
  • Application of Atomic Force Microscopy in Virology Research by Asylum Research
  • Apium 3D Printing Application Webinar

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SRC Partners with Sphere Fluidics

SRC is pleased to announce that we have signed an agreement with Sphere Fluidics, an established UK life sciences tools company, giving SRC the exclusive right to sell Sphere Fluidics products in Canada. Spun out from the University of Cambridge, Sphere Fluidics has won over 50 international business and innovation awards—and now has exclusive agreements with 11 distributors across the world.

Sphere’s impressive array of patented products – biochips and specialist chemicals –currently assist hundreds of customers globally with their research. Sphere has a range of novel single cell encapsulation instruments and consumables that perform high-throughput singe cell (and molecule) analysis. 

Cyto-Mine®

Sphere’s main platform, Cyto-Mine®, is the next generation single cell analysis system for antibody discovery and cell line development. Current processes for finding novel antibody targets or developing stable cell lines are time consuming and inefficient. Cyto-Mine® allows you to accelerate, automate and simplify your antibody discovery and cell line development workflows.

Within several hours, it can automatically screen tens of millions of single cells in miniaturised aqueous picoliter compartments called picodroplets. The picodroplets are assayed for single cells that secrete valuable proteins (e.g. antibodies) and imaged (for monoclonality assurance) during subsequent dispensing of “hits”. Cyto-Mine® is enabling, increases throughput and reduces costs and time for biopharmaceutical discovery and development. 

 Sphere Fluidics 1

Sphere Fluidics

Picodroplet Single Cell Assay and Isolation System 

Sphere Fluidics research instruments are designed to assist you in finding highly valuable and rare biological variants among vast cell populations. By increasing speed and reducing cost, their picodroplet technology can help you save resources while boosting your chances of success.

Sphere Fluidics currently has two research instruments that enable you to generate, sort, and retrieve picodroplets for a range of applications. These are the Picodroplet Single Cell Encapsulation System and the Picodroplet Single Cell Assay and Isolation System. Both are compatible with their range of microfluidic specialist chemicals and biochips, as well as other standard and custom biochips from other sources.

ESI-Mine™

ESI-Mine™ is a label-free platform for high-throughput, miniaturised electrospray injection mass spectrometry (ESI-MS). It can test up to 200,000 biomolecular samples (e.g. peptides, enzymes, antibodies, metabolites and small molecules) per day in miniaturized volumes of 500-700pL (picodroplets) facilitating more efficient screening and analysis in bioproduction or synthetic biology processes.

Applying this novel approach, researchers can create a large library of picodroplets containing microorganisms producing proteins or small molecules of interest for analysis. One major drawback of using MS in analysis is that samples are usually destroyed and cannot be retrieved. To overcome this total sample destruction by ESI-MS, Sphere has developed a unique microfluidics workflow where picodroplets are split into two replicate streams with identical clones, one stream is analyzed by ESI‐MS, and the second stream is subsequently ‘held’ and only those ‘hit’ daughter picodroplets sorted based on the result of the MS analysis.

Sphere Fluidics

Cyto-Cellect™ Human IgGκ Detection Kit

Sphere Fluidics’ Cyto-Cellect™ Human IgGκ Detection Kit, in combination with the Cyto-Mine® Single Cell Analysis System, offers a sensitive and robust assay ideal for streamlining cell isolation and titer determination. When picodroplets are formed during the Cyto-Mine® workflow, the Human IgGκ Detection probes are co-encapsulated with the cells to enable the detection of secreted IgG. The Cyto-Cellect™ Human IgGκ Detection Kit is a simple FRET assay that detects the presence of IgG with kappa light chain within picodroplets immediately after secretion from encapsulated cells. 

Sphere Fluidics customers

Sphere has an impressive list of customers in North America and around the globe who use their products and have published data at conferences or in scientific papers on their instruments. These include Janssen (US), GSK (UK and Spain), Merck (Germany), UCB (Belgium), Manchester University (UK) and Texas A&M (US).

Contact

Click here to contact SRC to learn more about Sphere Fluidics and their products.

 

Using contact angle measurements to study and QC surface treatments and coatings with Biolin Scientific

Biolin Scientific Webinar

Surface wettability and adhesion are vital phenomena in a variety of industries ranging from coatings industry to pharmaceutical and biomaterial industry. A simple and efficient contact angle measurement is often used for characterizing the water repellency and other properties such as how successful a surface treatment has been. In this webinar, we will go through the background and significance of different contact angles: where do they originate from, why are they important and how they can be measured in practice. We will give examples of situations where different kind of contact angle measurements are effective in characterizing the water repellency of a surface.

Upcoming Biolin Scientific Webinar

 

Join Spectra Research & Rokit for free webinar regarding cellular physiology of cancer cells in 3D

The cancer world isn’t flat: why cancer researchers adopt 3-D bioprinting

webinar regarding cellular physiology

The growing push for 3-D tissue models is limited by challenges in automated handling, processing and scalability of the technology to various types of materials and high-throughput applications. To meet these challenges, ROKIT Healthcare has developed all-in-one bioprinting platforms and human-cell derived ECM bioinks that allow researchers to biologically mimic the formation of complex, heterogeneous 3-D structures and to scale the technology to high-throughput applications. This webinar will focus on the platform’s usage in cancer biology. It will discuss evidence for 3-D bioprinting capturing altered proliferation and cell morphology profiles, revealing more realistic drug responses, and mimicking vascularized tumor microenvironments – to suggest why bioprinting of cancer cells is a scientifically rigorous method to generate physiologically relevant cancer models for preclinical screening and testing, as well as for new therapy research. You will learn about:
– Key advantages of 3D bioprinting over other techniques
– Five alterations in cellular physiology of cancer cells in 3D vs. 2D
– Evaluation of how 3D bioprinted tissues have altered proliferation and cell morphology
– Evaluation of how 3D bioprinted tissues reveal more realistic drug responses
– Evaluation of how 3D bioprinted tissues mimic complex tumor-immune microenvironments
– Built-in cell incubator, diverse material use, and high-throughput capabilities of ROKIT Healthcare’s all-in-one bioprinting platform Dr. INVIVO 4D6

photo of Dr. Sanjay Gupta

Dr. Sanjay Gupta

Professor & Research Director

Dr. Sanjay Gupta is a Professor & Research Director and holds Carter Kissell Endowed Chair in Urologic Oncology in the Department of Urology at Case Western Reserve University and The Urology Institute at the University Hospitals Case Medical Center. Dr. Gupta’s research focuses on understanding the risk factors and mechanisms of prostatic and bladder diseases, develop appropriate biomarkers for early detection and prognosis, identify novel targets to monitor the efficacy of various synthetic and natural agents and develop them as chemo preventatives/therapeutics Dr. Gupta has authored some 150 publications, including book chapters, research articles and reviews, and has spoken at several occasions in cancer prevention symposium, seminars and meetings. He has been serving in various study sections at National Cancer Institute (NCI) and Department of Defense (DOD), and other councils around the globe.

Madhuri Dey

Madhuri Dey

Ph.D Candidate @Ibrahim Ozbolat Lab – Penn State University
Talk Title: 3D BIOPRINTING OF THE CANCER MICROENVIRONMENT
Da-Yae Lee

Da-Yae Lee

Senior Bio-Consultant @ROKIT Healthcare
Talk Title: ALL-IN-ONE BIOFABRICATION IS THE KEY TO UNRAVELING CANCER COMPLEXITIES

 

Sensofar presents applications for Archeology & Paleontology!

Sensofar presents applications

Sensofar Applications: Archeology & Paleontology

WEBINAR DATE:
Wednesday October 28, 2020
11:00 AM – 12:00 PM EDT

 

How can an optical profiler help to discover the diets of extinct species? And how did our ancient ancestors use tools in the Stone Age? These and other questions will be answered during this session, which we will be covering the Sensofar solutions for archaeology, paleontology and related fields of science.
Several applications will be presented such as the use of scale-sensitive fractal analysis in microwear studies, showing the advantages of our 3-in-1 technology. We want to show you how we helped make this amazing science easier, faster and more reliable.


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David Paez
Sensofar Metrology

Received bachelor’s degree in Engineering Physics at Polytechnic University of Catalonia (UPC) and MSc in Nanoscience and Nanotechnology at University of Barcelona (UB). As a Sales Specialist, I’ve helped customers all around the world to choose Sensofar’s systems, no matter the field they are in. Some of my duties are to communicate Sensofar’s knowledge about optical metrology and train our customers on how to extract all the potential from our 4-in-1 technology equipment.