Upcoming Webinar – Contact Resonance Tools for AFM Nanomechanics

Donna Hurley, National Institute of Standards & Technology
Roger Proksch, Asylum Research, an Oxford Instruments Company

ContactResonanceNanoscale information on mechanical properties is critical for many advanced materials and nanotechnology applications. Atomic Force Microscopy techniques for probing mechanical properties of samples in the nanometer range have emerged over the past decades. In contrast to the large number of techniques for softer samples, few techniques are capable of measuring moduli in the 1-200 GPa range. One technique, Contact Resonance (CR), has proven to work very well in this range. CR methods operate in contact mode with dynamic excitation near a cantilever resonant frequency, enabling sensitive measurements over a wide range of materials. Moreover, analysis of the CR peak frequency and quality factor yields accurate, quantitative data on elastic modulus and viscoelastic damping.

In this webinar, we’ll explain the basic concepts of measurements with different CR approaches including:

• Point spectroscopy
• Qualitative contrast imaging
• Quantitative mapping

We’ll also discuss practical implementation of contact resonance to a variety of samples and some of the pitfalls and artifacts you might encounter. Finally, we’ll present results on how CR methods have been used to improve understanding of systems such as:

• Composites
• Thin films
• Biomaterials
• Polymer blends

The nanomechanical characterization capabilities of CR methods, as you will come to learn, are an essential tool for the development, production, and in-situ monitoring of today’s and tomorrow’s materials.

Click here to register

Free Webinar May 22 Getting Started with AFM in Biology – It’s Easier Than You Think

DNAHelix.093645Register Now8:00-9:00am PDT
​4:00-5:00pm PDT

You may be a biologist new to the AFM or an AFM expert starting to study biology. When you first start out, using an AFM for biological applications can seem overwhelming. Although there are challenges for successful AFM in biology, we’ll show you it’s easier than you think!

Sample prep is a critical part of successful Bio-AFM. There are some basic principles that help insure success. However, life is complex and so are biological samples – with variations as large as the number of researchers. Thus, at the same time, you will need to be flexible – your samples may require a prep that is tweaked and tailored a bit to optimize your results. Working in liquid adds another challenge. In addition, the choice of measurement mode may not be obvious. Do I want to use tapping mode? Force curves? Contact Mode? Finally, there is a long list of commercial cantilevers available and choosing the best one can be like looking for a needle in a haystack.

The Webinar presents four case studies of typical biological samples

1. Imaging DNA in liquid – including routine helix resolution
2. Imaging living cells in liquid
3. Measuring Young’s modulus of living cells
4. Unfolding forces in Titin

In each case we will discuss sample prep, lever and measurement mode choice and follow up with data interpretation and cautionary examples of experimental artifacts. The goal of this webinar is to give you the confidence to repeat these experiments yourself and then extending them to fit your own research.

About the lecturer

Irene Revenko is one of the world’s leading experts in Bio AFM. She is a staff scientist at Asylum Research and has over 19 years of AFM experience. She initiated the first bio-classes at Asylum Research in 2002 and since then has taken many students from their first AFM measurements through cutting edge results.

Register Now

Witec Workshop – May 24th, 2013

WITec 3D Raman Imaging Meets AFM, SNOM and Profilometry Workshop. May 24th, 2013 – Université de Montréal

This workshop will give a detailed introduction to the operational principles and instrumental configurations relevant to confocal Raman and Scanning Probe Microscopy (AFM, SNOM, Pulsed Force Mode). Our Speakers will cover several aspects of Raman and SPM imaging and their fields of applications. An extensive system demonstration gives the participants the opportunity to see this knowledge applied using an alpha300 RSA (combined AFM & SNOM Confocal Raman Microscope).

Scientists interested in how to chemically identify and image the compounds of a sample at the highest spatial resolution are invited to participate. Typical research fields for confocal Raman imaging are nanotechnology, pharmaceutics and cosmetics, materials and polymer sciences, archaeology and geoscience, forensics, coatings, thin films and all fields where a clear identification of the distribution of chemical compounds is a necessity.


Friday, 24th May 2013
09.30 Welcome
09.45 Wei Liu – Introduction to Confocal Raman Imaging
10.15 Sylvain Cloutier – Hybrid Nanocrystal-based Heterostructures for Opto-Electronis
10.45 Klaus Weishaupt – 3D Raman Imaging Meets AFM, SNOM and Profilometry
11.30 Jean-Francois Masson – Characterization of photonics nanomaterials for plasmonic sensors
12.00 Lunch & Equipment Demonstration

The workshop is free of charge but it requires registration due to limited availability of places. In order to register, please contact Murielle Johnson at muriellej@aca.ca or 905-502-2088

Click here and download the May 24th 3D Raman Imaging Meets AFM, SNOM and Profilometry Workshop PDF for full program details.

Are you interested in learning more about twin-screw processes in the pharmaceutical industry?

Sign up for our free webinar: Twin Screw Processes in Pharma

Webinar date:

Tuesday April 16, 2013

Webinar Time:
Session 1 (Asia-Pacific) – 3:00 p.m. (CST)
Session 2 (Europe) – 2:00 p.m. (CEST)
Session 3 (North America) – 11:00 a.m. (EDT)

Webinar Duration:
45 minutes in length, followed by a question and answer period.

To register please click here


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Free Webinar: Twin Screw Processes in Pharma – An Introduction

Scientists, engineers and managers in research, process development and production, desiring a glimpse into the various areas of application for twin screw extruders in the pharmaceutical industry.

Hot Melt Extrusion (HME) has been advancing for a number of years for formulating active ingredients with low solubility. The HME process will be presented and discussed in detail using practical examples. The use of the extruder will be presented for moisture extrusion and granulation.

Application specialists for the pharmaceutical industry.


Tuesday April 16, 2013

Session 1 (Asia-Pacific) – 3:00 p.m. (CST – China Standard Time)
Session 2 (Europe) – 2:00 p.m. (CEST – Central European Summer Time)
Session 3 (North America) – 11:00 a.m. (EDT – Eastern Daylight Time)

45 minutes in length, followed by a question and answer period.

Click here to register

Understanding food on the microscale – a free webinar

Technicians skilled in developing, characterizing and testing food and its processability, and with an understanding of rheology, will be interested in the complimentary webinar being offered by Thermo Scientific on November 13, 2012.

Combining rheology with other analytical techniques allows for a better understanding of the flow and behaviour of food products. The combined results can correlate specific macroscopic flow and application phenomena with micro/molecular structure. These methods can be used for:

– time and temperature dependent behaviour, gelatinization, gelification, cross-linking, crystallization, melting and freezing

– particle size and particle size distribution

– aggregation and disaggregation, thixotropy

– correlation with microstructure via in-situ microscopy

– mouth feeling, spreadability and processability


Date and time:

Tuesday, November 13, 2012 at 11 a.m. EDT




1 hour

Thermo Scientific provides material characterization solutions that analyze and measure viscosity, elasticity, processability and temperature-related mechanical changes of plastics, food, cosmetics, pharmaceuticals and coatings, chemical or petrochemical products, plus a wide variety of liquids or solids.

Please visit the Thermo Scientific website to register.

Introducing the New Environmental Scanner for the Cypher™ AFM – the Highest Resolution Fast Scanning AFM

Imagine an AFM that routinely images the DNA double helix (top image) and atomic point defects (bottom) – in any environment.

We invite you to Booth 510 at the MRS Fall Meeting for an exclusive preview of the new Environmental Scanner for Cypher.

The Cypher Environmental Scanner is a modular and customizable platform with sample temperature control in a wide spectrum of environments. The Environmental Scanner is designed around a sealed cell which can sustain moderate positive pressures and uses chemically inert materials, such as fused silica and FFKM, to provide a controlled environment while maintaining accurate and distortion free imaging.

Cypher offers the widest range of scanning environments:

  • Buffers, solvents, inert gases, strong acids/bases
  • Liquid/gas perfusion
  • Continuous liquid flow
  • Temperature control from 0°C to 250°C
  • Optional electrical feedthroughs

If your experiments require a glove box, Cypher can also be operated in this configuration.

MFP-3D™ AFM – High Resolution,
Closed-loop Precision, and Flexibility

We’ll also be featuring the MFP-3D, the most versatile AFM platform with numerous environmental accessories and advanced scanning modes. The MFP-3D can be configured as:

Both the MFP-3D and Cypher AFMs scan with all standard AFM imaging modes (tapping, contact, MFM, phase, etc.), and numerous exclusive imaging modes:


LYON, FRANCE – JUNE 21-26, 2015

Calorimetry and thermal analysis methods, alone or linked to other techniques, will be described and applied to the characterization of catalysts, oxides, metals, supports, adsorbents, polymers, composites, food, pharmaceuticals, mesoporous solids, ionic liquids, phase change materials, heat storage materials, hydrogen storage materials. Examples will be given in various domains: catalytic reactions, air and wastewater treatment, clean and renewable energies, refining of hydrocarbons, green chemistry, hydrogen production and storage, CO2 capture, interseasonal heat storage, food chemistry, polymers…