Reichert now offers a complete setup for performing electrochemistry measurements in combination with SPR (ESPR). In addition to the SR7500DC SPR system and Reichert’s three-electrode electrochemistry flow cell, this platform includes a high quality and versatile potentiostat from Princeton Applied Research (PAR), the VersaSTAT 4 that is ideal for carrying out SPR-related electrochemistry experiments. The excellent low current performance of the VersaSTAT 4 coupled with the high sensitivity of the Reichert SR7500DC system provides superior detection of ESPR events.
The VersaSTAT 4 is an extremely versatile and precise potentiostat. It has excellent low current performance with fA resolution and pA accuracy. Other key features include:
Combining electrochemistry with SPR allows the concurrent reading of both optical and electrochemical properties occurring at the sensor chip surface. Surface effects that are commonly explored include thin film formation (SAM), adsorption/desorption, polymer growth, redox-initiated conformation changes and trace metals. Since SPR is sensitive to the adsorbed layer on the gold electrode and to the dielectric properties of the solution phase, electrochemically modulated diffusion layers can also be detected by SPR.