905-890-0555

Discount Products: Look through products available for a 25% – 50% discount in 2020. The items provided on a first come, first serve basis.
View Discounted Products

Brookhaven Instruments NanoBrook ZetaPALS

Zeta Potential Analyzer using Phase Analysis Light Scattering

  • Zeta potential for difficult applications:
    • For proteins, peptides, mAb, RNA, and other biological samples
    • For zeta potential in organic solvents
    • For oily or viscous media
    • For high-salt suspensions
    • For samples near the I.E.P.
  • PALS: 1,000 times more sensitive than other techniques
  • Disposable cuvettes, no contamination or alignmnent
  • Built-in automatic procedures and parameters (SOP)

 

Request a Quote



Introducing the Brookhaven Instruments NanoBrook ZetaPALS

Brookhaven can handle your difficult applications with high sensitivity

For measurements of very low mobilities, the NanoBrook ZetaPALS is the answer. The only answer! With concepts developed at Bristol University and Brookhaven Instruments, the NanoBrook ZetaPALS determines zeta potential using Phase Analysis Light Scattering: A technique that is up to 1,000 times more sensitive than traditional light scattering methods based on the shifted frequency spectrum.

Electrostatic repulsion of colloidal particles is often the key to understanding the stability of any dispersion. A simple, easy measurement of the electrophoretic mobility, even in nonpolar liquids, yields valuable information. Measurements made in water and other polar liquids are easy and fast with the NanoBrook ZetaPlus. Such measurements cover the range of typically ± (6 to 100) mV, corresponding to mobilities of ± (0.5 to 8) x 10-8 m2 /V·s. The NanoBrook ZetaPALS covers this full range, of course, and extends it by a factor of 1000 in sensitivity!

Principles of Operation

The NanoBrook ZetaPALS utilizes phase analysis light scattering to determine the electrophoretic mobility of charged, colloidal suspensions. Unlike its cousin, Laser Doppler Velocimetry (LDV) (sometimes called Laser Doppler Electrophoresis (LDE)), the PALS technique does not require the application of large fields which may result in thermal problems or denaturation. During a phase shift measurement, the particles need only to move a fraction oftheir own diameter to yield good results. In salt concentrations up to 3 molar and with electric fields as small as 1 or 2 V/cm, enough movement is induced to get excellent results. In addition, the Autotracking feature compensates for thermal drift.

 

Brookhaven Instruments NanoBrook ZetaPALS



Brookhaven Instruments NanoBrook ZetaPALS

Key Features

Zeta Potential

Zeta Potential Analyzer using Phase Analysis Light Scattering

  • Zeta potential for difficult applications:
    • For proteins, peptides, mAb, RNA, and other biological samples
    • For zeta potential in organic solvents
    • For oily or viscous media
    • For high-salt suspensions
    • For samples near the I.E.P.
  • PALS: 1,000 times more sensitive than other techniques
  • Disposable cuvettes, no contamination or alignmnent
  • Built-in automatic procedures and parameters (SOP)


Key Benefits

Clear and Simple Presentation

The figure below shows the results of an actual experiment with a NanoBrook ZetaPALS instrument. The important parameters and results are seen at a glance. The excellent agreement of the five runs in this experiment is obvious with low standard error and superb overlay of curves. With Brookhaven instruments Particle Solutions Software Suite, the user can easily produce a customized report, or select from one of the pre-designed templates. Furthermore, exportation of data to multiple formats (i.e: XLS, CSV, PDF) is both quick and simple.

 


Brookhaven Instruments NanoBrook ZetaPALS


Trust the Experts at Spectra Research Corporation

Spectra Research Corporation (SRC) offers a range of innovative high-quality scientific products and laboratory services to industrial and scientific markets throughout Canada.

Specifications

Sample Type Most proteins, nanoparticle and colloidal-sized materials, suspended in any non-absorbing liquid, with relative permittivity (dielectric constant) > 1.5 and viscosity < 30 cP.
Size Range suitable for zeta measurement 1nm to 100 µm, sample dependent
Mobility Range 10-11 to 10-7 m2 /V*s
Zeta potential range -500 mV to 500 mV, sample dependent
Maximum sample conductivity 220 mS/cm, covering saline and PBS solutions for proteins
Sample Cells 210 µL, 450 µL, 1250 µL
Maximum sample concentration 40% v/v, sample dependent
Signal Processing Electrophoretic & Phase Analysis Light Scattering, ELS & PALS
Precision ± 3%, depending on salt concentration
Data Presentation Doppler Frequency Shift, electrophoretic mobility, zeta potential using Smoluchowski, Hückel, or Henry
Temperature Control -5 ° C to 110 ° C, ± 0.1 ° C, active control. No external circulator required.
Condensation Control Purge facility using dry air, nitrogen preferred
Standard Laser 40 mW 640 nm temperature-controlled red semiconductor laser. Alternative wavelengths available.
Scattering Angle  15°
Compliance ISO13321 and ISO22412 compliant results for sizing
Power Requirements 100/115/220/240 VAC, 50/60 Hz, 150 Watts
Dimensions 23.3 x 42.7 x 48.1 cm (HWD)
Weight 15 kg
Environmental Characteristics Temperature 10 °C to 75 °C Humidity 0% to 95%, non-condensing
CE Certificate Class I laser product, EN 60825-1:2001, CDRH
Maximum sample concentration 40% v/v, sample dependent

 

Datasheet


Contact Spectra Research

Address

3585 Laird Rd., Unit 15 & 16,
L5L 5Z8 Mississauga
Ontario
Canada

Phone :  905-890-0555

Toll Free : 1-866-753-4433
Fax :  905-890-1959

Email: info@spectraresearch.com

About Spectra Research

Spectra Research Corporation (SRC) offers a range of innovative high-quality scientific products and laboratory services to industrial and scientific markets throughout Canada.

Established in 1993, SRC is a subsidiary of Allan Crawford Associates (ACA), one of Canada’s largest distributors of electronic components, test equipment and integrated networking solutions.

Spectra Research Location

Top