Thermo Scientific Pharma 16 Twin-Screw Extruder

Thermo Scientific Pharma 16 Twin-Screw Extruder

  • 2-in-1 process design – quickly disassemble parts for easy cleaning and process switching from HME to TSG.
  • Simple continuous process integration – plug-and-play functionality with upstream and downstream process equipment (e.g., feeders, chill rolls, pelletizers, dryers, etc) simplifies production line design.
  • Less optimization time, cost and effort – extruder process parameters are scaleable to larger Thermo Scientific extruders due to geometric similarity with minimal use of expensive ingredients.

 




Introducing the Thermo Scientific Pharma 16 Twin-Screw Extruder

The Pharma 16 Twin-Screw Extruder is ideal for pilot-scale, continuous HME or TSG processes used for research, development or production in the pharmaceutical industry. Companies can bring products to market faster and with high quality by developing a continuous process for solid dosage forms compared to a batch process. Effects of pilot-scale process conditions on drug formulations for drug delivery and pharmaceutics can easily be studied using the Pharma 16 Twin-Screw Extruder.

Thermo Scientific Pharma 16 Twin-Screw Extruder



Thermo Scientific Pharma 16 Twin-Screw Extruder

Key Features

Pharma 16 Twin-Screw Extruder highlights:

  • 2-in-1 process design – quickly disassemble parts for easy cleaning and process switching from HME to TSG.
  • Simple continuous process integration – plug-and-play functionality with upstream and downstream process equipment (e.g., feeders, chill rolls, pelletizers, dryers, etc) simplifies production line design.
  • Less optimization time, cost and effort – extruder process parameters are scaleable to larger Thermo Scientific extruders due to geometric similarity with minimal use of expensive ingredients.

 



Key Benefits

Rapidly develop pharmaceutical formulations and adopt continuous processing methods using the Thermo Scientific™ Pharma 16 Twin-Screw Extruder.  The Pharma 16 Twin-Screw Extruder can switch between continuous hot melt extrusion (HME) or wet granulation (TSG) with ease. Optimize drug process development parameters with less time and effort than batch processes and easily scale-up to larger Thermo Scientific™ extruders with using minimal amounts of expensive APIs and excipients.


Thermo Scientific Pharma 16 Twin-Screw Extruder


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Specifications

Catalog number Unit Size Description Price (CAD)
553-1040 Pharma 16 Twin-Screw Extruder

Barrel Barrel Length 40:1 L/D
7 barrel zones (1st zone permanent cooled) + 1 die heater
Pressure 150 bars (option)
Center Line Spacing 1050 mm
Length (English) Screw length: HME L/D = 40 (40x16mm = 640mm)
TSG L/D = 40.75 (40.75x16mm = 652mm)
Speed 10-1000 rpm
Temperature (Metric) Operating HME: 10-300°C / TSG: 10-100°C
Throughput HME: 0.5-5 kg/h / TSG: 1-15 kg/h (depending on formulation)
Description Pharma 16 Twin-Screw Extruder
Max. Torque 36 Nm (2 screws, 18 Nm each)
Weight (Metric) 350 kg
Power Supply 400V 3Ph +N + PE (+/- 10%)
Dimensions (L x W x H) 1750mm x 610mm x 1220mm
Protection IP 54
Max. Screw Speed 1,000 rpm
Unit Size
Datasheet