Thermo Scientific™ Pharma 11 Twin-screw Extruder

Thermo Scientific™ Pharma 11 Twin-screw Extruder

  • Uses smaller material quantities for faster, cost-effective development
  • Converts easily from hot melt extrusion (HME) to twin screw granulation (TSG) applications
  • Operates at throughput ranges from 20g/h up to 2.5kg/h
  • Processing length: L/D ratio 40:1
  • Screw elements and barrel design scale geometrically across the all Thermo Scientific Pharma Extruders and allow easy process scale-up
  • Easy-to-operate with user-friendly, intuitive touch screen with integrated feeder control
  • Maximize lab space with small footprint machine
  • Perfect for glove box or isolator applications with removable touch screen
  • All material contact parts are easily removable
  • Documentation of extrusion parameters and suitable for process analytical technology (PAT)
  • GMP-compliant, full validation available: FAT, SAT, IQ/OQ

 




Introducing the Thermo Scientific™ Pharma 11 Twin-screw Extruder

Perform material- and labor-effective extrusion with Thermo Scientific™ Pharma 11 Twin-screw Extruder, which requires only a small amount of active pharmaceutical ingredient, operating at throughput levels as low as 20g/h.

Thermo Scientific™ Pharma 11 Twin-screw Extruder



Thermo Scientific™ Pharma 11 Twin-screw Extruder

Key Features

The Pharma 11 Twin-screw Extruder Features:

  • Uses smaller material quantities for faster, cost-effective development
  • Converts easily from hot melt extrusion (HME) to twin screw granulation (TSG) applications
  • Operates at throughput ranges from 20g/h up to 2.5kg/h
  • Processing length: L/D ratio 40:1
  • Screw elements and barrel design scale geometrically across the all Thermo Scientific Pharma Extruders and allow easy process scale-up
  • Easy-to-operate with user-friendly, intuitive touch screen with integrated feeder control
  • Maximize lab space with small footprint machine
  • Perfect for glove box or isolator applications with removable touch screen
  • All material contact parts are easily removable
  • Documentation of extrusion parameters and suitable for process analytical technology (PAT)
  • GMP-compliant, full validation available: FAT, SAT, IQ/OQ


Key Benefits

The parallel 11mm twin screws and compact design of the Pharma 11 Twin-screw Extruder is fully scalable with the Thermo Scientific stand-alone pharmaceutical compounding systems. Together, you can obtain process relevant results or even perform small scale production.

If you need a complete extrusion solution, a wide range of accessories are available for the Pharma 11 Twin-screw Extruder, including volumetric and gravimetric feeders, a conveyor belt and a pelletizer.


Thermo Scientific™ Pharma 11 Twin-screw Extruder


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Specifications

Catalog number Unit Size Description Price (CAD)
553-0020 Each Pharma 11 HME; 40:1, 1000rpm

Feed Zones Permanent liquid cooled feeding port
Max. Temperature 280°C
Heating Zones 7 x 5 L/D heat/cool zones, +1 heating zone for die
Width (Metric) 50cm
Height (Metric) 41cm
Pressure 100 bar, safety monitored
Screw Diameter (Metric) 11mm
Length (Metric) 90cm
Screw Type co-rotating parallel twin-screw
Speed Variable speed drive system 10 to 1000rpm
Material Pharma grade stainless steel Boehler M340
Temperature (Metric) Operating 10 °C to 280 °C (with appropriate cooling device)
Throughput 20 g/h up to 2.5kg/h
Description Pharma 11 HME; 40:1, 1000rpm
Diameter (Metric) 11mm
Max. Torque 6 Nm per shaft, constant torque, safety monitored
Item Description Pharma 11 HME; 40:1, 1000rpm
Weight (Metric) 55kg
Max. Screw Speed 1000rpm
Unit Size Each
553-0138 Each Pharma 11 Controlled Cooling 40:1 (Bottom Barrel only)

Description Pharma 11 Controlled Cooling 40:1 (Bottom Barrel only)
Unit Size Each
553-0400 Each Pharma 11 Volumetric Single Screw Feeder

Description Pharma 11 Volumetric Single Screw Feeder
Unit Size Each
553-0600 Each Pharma 11 Air Cooled Conveyor

Description Pharma 11 Air Cooled Conveyor
Unit Size Each
553-0610 Each Pharma 11 Varicut Pelletizer

Description Pharma 11 Varicut Pelletizer
Unit Size Each
5530276 Each TSG Conversion Kit For Pharma 11 HME

Description TSG Conversion Kit For Pharma 11 HME
Unit Size Each
Datasheet